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1

Large Systems Change: An Emerging Field of Transformation and Transitions

Waddell, Steve, Waddock, Sandra, Cornell, Sarah, Dentoni, Domenico, McLachlan, Milla, Meszoely, Greta

Journal:

Journal of Corporate Citizenship

Year:

2015

Language:

english

File:

PDF, 686 KB

english, 2015

2

D-penicillamine-associated myasthenia gravis: Immunological and electrophysiological studies

Dr. Peter R. W. Fawcett, Dr. Sandra M. McLachlan, Dr. Louise V. B. Nicholson, Dr. Zohar Argov, Dr. Frank L. Mastaglia

Journal:

Year:

1982

Language:

english

File:

PDF, 637 KB

english, 1982

3

Cyclosporin A promotes spontaneous outgrowth in vitro of Epstein–Barr virus-induced B-cell lines

Bird, A. Graham, McLachlan, Sandra M., Britton, Sven

Journal:

Year:

1981

File:

PDF, 212 KB

1981

4

Distribution of sympathetic neuroeffector junctions in the juxtaglomerular region of the rabbit kidney

Susan E. Luff, Sandra G. Hengstberger, Elspeth M. McLachlan, W.P. Anderson

Journal:

Journal of the Autonomic Nervous System

Year:

1992

Language:

english

File:

PDF, 6.18 MB

english, 1992

5

Breaking Tolerance to Thyroid Antigens: Changing Concepts in Thyroid Autoimmunity

McLachlan, Sandra M., Rapoport, Basil

Journal:

Endocrine Reviews

Year:

2014

Language:

english

File:

PDF, 1.52 MB

english, 2014

6

Thyroid Peroxidase as an Autoantigen

McLachlan, Sandra M., Rapoport, Basil

Journal:

Year:

2007

Language:

english

File:

PDF, 8.57 MB

english, 2007

7

Thyrotropin-Blocking Autoantibodies and Thyroid-Stimulating Autoantibodies: Potential Mechanisms Involved in the Pendulum Swinging from Hypothyroidism to Hyperthyroidism or Vice Versa

McLachlan, Sandra M., Rapoport, Basil

Journal:

Year:

2013

Language:

english

File:

PDF, 408 KB

english, 2013

8

Graves' Hyperthyroidism Is Antibody-Mediated But Is Predominantly a Th1-Type Cytokine Disease

Rapoport, Basil, McLachlan, Sandra M.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2014

Language:

english

File:

PDF, 36 KB

english, 2014

9

Vitamin D Deficiency in Mice Impairs Colonic Antibacterial Activity and Predisposes to Colitis

Lagishetty, Venu, Misharin, Alexander V., Liu, Nancy Q., Lisse, Thomas S., Chun, Rene F., Ouyang, Yi, McLachlan, Sandra M., Adams, John S., Hewison, Martin

Journal:

Year:

2010

Language:

english

File:

PDF, 402 KB

english, 2010

10

Antibodies to Thyroid Peroxidase Arise Spontaneously with Age in NOD.H-2h4 Mice and Appear after Thyroglobulin Antibodies

Chen, Chun-Rong, Hamidi, Sepehr, Braley-Mullen, Helen, Nagayama, Yuji, Bresee, Catherine, Aliesky, Holly A., Rapoport, Basil, McLachlan, Sandra M.

Journal:

Year:

2010

Language:

english

File:

PDF, 405 KB

english, 2010

11

Variable Effects of Dietary Selenium in Mice That Spontaneously Develop a Spectrum of Thyroid Autoantibodies

McLachlan, Sandra M, Aliesky, Holly, Banuelos, Bianca, Hee, Shane S Que, Rapoport, Basil

Journal:

Year:

2017

Language:

english

File:

PDF, 955 KB

english, 2017

12

Deborah Doniach: Discovering Thyroid Autoimunity; the end of horror autotoxicus

Bahn, Rebecca S, Doniach, Tabitha, McLachlan, Sandra

Journal:

Year:

2020

File:

PDF, 1.11 MB

2020

13

Role of MHC class I expression and CD8+ T cells in the evolution of iodine-induced thyroiditis in NOD-H2h4 and NOD mice

Suman Verma, Patricia Hutchings, Jin Guo, Sandra McLachlan, Basil Rapoport, Anne Cooke

Journal:

European Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 593 KB

english, 2000

14

Heterogeneity of organ-specific autoimmune diseases

Sandra M. McLachlan, Basil Rapoport

Journal:

Immunology Today

Year:

1995

Language:

english

File:

PDF, 142 KB

english, 1995

15

Combinatorial libraries: new insights into human organ-specific autoantibodies

Basil Rapoport, Stefano Portolano, Sandra M. McLachlan

Journal:

Immunology Today

Year:

1995

Language:

english

File:

PDF, 1.04 MB

english, 1995

16

A powerful role for B cells and autoantibodies in disease

Sandra M McLachlan, Basil Rapoport

Journal:

Immunology Today

Year:

2000

Language:

english

File:

PDF, 98 KB

english, 2000

17

Insight into thyrotropin receptor cleavage by engineering the single polypeptide chain luteinizing hormone receptor into a cleaving, two subunit receptor

Gregorio D. Chazenbalk, Sandra M. McLachlan, Chun-Rong Chen, Basil Rapoport

Journal:

Year:

2001

Language:

english

File:

PDF, 738 KB

english, 2001

18

Thyroid stimulating monoclonal antibodies: overcoming the road blocks and the way forward

Sandra M. McLachlan, Basil Rapoport

Journal:

Clinical Endocrinology

Year:

2004

Language:

english

File:

PDF, 187 KB

english, 2004

19

Thyroid peroxidase autoantibody epitopes revisited

Sandra M. McLachlan, Basil Rapoport

Journal:

Clinical Endocrinology

Year:

2008

Language:

english

File:

PDF, 54 KB

english, 2008

20

Cathepsin S is not crucial to TSHR processing and presentation in a murine model of Graves' disease

Mrinalini Kala, Chun-Rong Chen, Sandra M. McLachlan, Basil Rapoport, Holly Aliesky, Harold A. Chapman

Journal:

Year:

2005

Language:

english

File:

PDF, 367 KB

english, 2005

21

Autoimmune hypothyroidism: T cells caught in the act

McLachlan, Sandra M, Rapoport, Basil

Journal:

Nature Medicine

Year:

2004

Language:

english

File:

PDF, 318 KB

english, 2004

22

Thyroid Peroxidase Autoantibodies of IgE Class in Thyroid Autoimmunity

Jin Guo, Basil Rapoport, Sandra M. McLachlan

Journal:

Clinical Immunology and Immunopathology

Year:

1997

Language:

english

File:

PDF, 105 KB

english, 1997

23

The Epitopic “Fingerprint” of Thyroid Peroxidase-Specific Fab Isolated from a Patient's Thyroid Gland by the Combinatorial Library Approach Resembles That of Autoantibodies in the Donor's Serum

Juan Carlos Jaume, Jin Guo, Ayumu Kakinuma, Basil Rapoport, Sandra M. McLachlan

Journal:

Clinical Immunology and Immunopathology

Year:

1997

Language:

english

File:

PDF, 167 KB

english, 1997

24

The development of large primordia inVicia fabaL.: Some cytological and anatomical changes

Ronald D. MacLeod, Sandra M. McLachlan

Journal:

Year:

1975

Language:

english

File:

PDF, 746 KB

english, 1975

25

Lateral root elongation inVicia fabaL.

Ronald D. MacLeod, Sandra M. McLachlan

Journal:

Year:

1974

Language:

english

File:

PDF, 750 KB

english, 1974

26

Autoantibody-mediated capture and presentation of autoantigen to T cells via the Fcε receptor by a recombinant human autoantibody Fab converted to IgE

Jin Guo, Sonia Quaratino, Juan Carlos Jaume, Giuseppe Costante, Marco Londei, Sandra M. McLachlan, Basil Rapoport

Journal:

Journal of Immunological Methods

Year:

1996

Language:

english

File:

PDF, 1.10 MB

english, 1996

27

Chemical carcinogen induction of DNA-repair synthesis in human peripheral blood monocytes

Robert S. Lake, Melvin L. Kropko, Sandra McLachlan, Mary R. Pezzutti, Robert H. Shoemaker, Howard J. Igel

Journal:

Mutation Research/Environmental Mutagenesis and Related Subjects

Year:

1980

Language:

english

File:

PDF, 1.01 MB

english, 1980

28

Clinical virology for community hospitals

Richard B. Thomson Jr., Cynthia C. Bostick, MT (ASCP), Sandra S. McLachlan, MT (ASCP)

Journal:

Clinical Microbiology Newsletter

Year:

1991

Language:

english

File:

PDF, 289 KB

english, 1991

29

Atypical T lymphoproliferative disorder demonstrating in vitro suppressor and helper characteristics

S. J. Proctor, A. M. McGregor, Jane Clark, Sandra McLachlan, Anne Dickinson

Journal:

British Journal of Haematology

Year:

1982

Language:

english

File:

PDF, 561 KB

english, 1982

30

Is Receptor Cleavage into Two Subunits Necessary for Thyrotropin Action?

Gregorio D. Chazenbalk, Sandra M. McLachlan, Yuji Nagayama, Basil Rapoport

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 198 KB

english, 1996

31

Cross-reactive Idiotypes on High Affinity IgG Class Human Monoclonal Thyroglobulin Autoantibodies

Peter J. Delves, Sandra M. McLachlan, Elizabeth Drewe, Nao Fukuma, Vaughan B. Petersen, Bernard Rees Smith

Journal:

Journal of Autoimmunity

Year:

1993

File:

PDF, 468 KB

1993

32

Human thyroperoxidase folds in one complex B-cell immunodominant region

Stéphanie Blanchin, Valérie Estienne, Jin Guo, Basil Rapoport, Sandra M McLachlan, Pierre Carayon, Jean Ruf

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 193 KB

english, 2002

33

The shed thyrotropin receptor is primarily a carboxyl terminal truncated form of the A subunit, not the entire A subunit

Kunihiko Tanaka, Gregorio D Chazenbalk, Sandra M McLachlan, Basil Rapoport

Journal:

Molecular and Cellular Endocrinology

Year:

1999

Language:

english

File:

PDF, 213 KB

english, 1999

34

Profile of lambda light chain variable region genes in graves' orbital tissue

Mark F. Prummel, Gregorio Chazenbalk, Juan Carlos Jaume, Basil Rapoport, Sandra M. McLachlan

Journal:

Molecular Immunology

Year:

1994

Language:

english

File:

PDF, 992 KB

english, 1994

35

Kinetics of immunoglobulin production by cultured human peripheral blood lymphocytes

Sandra M. McLachlan, Bernard Rees Smith, Reginald Hall

Journal:

Journal of Immunological Methods

Year:

1978

Language:

english

File:

PDF, 312 KB

english, 1978

36

The Link between Graves’ Disease and Hashimoto’s Thyroiditis: A Role for Regulatory T Cells

McLachlan, Sandra M., Nagayama, Yuji, Pichurin, Pavel N., Mizutori, Yumiko, Chen, Chun-Rong, Misharin, Alexander, Aliesky, Holly A., Rapoport, Basil

Journal:

Year:

2007

Language:

english

File:

PDF, 951 KB

english, 2007

37

Why Measure Thyroglobulin Autoantibodies Rather Than Thyroid Peroxidase Autoantibodies?

McLachlan, Sandra M., Rapoport, Basil

Journal:

Year:

2004

Language:

english

File:

PDF, 3.10 MB

english, 2004

38

Antibodies Focused on the Human Autoantibody Immunodominant Region Are Induced by B Lymphocytes that Constitutively Express Thyroid Peroxidase Diverted to the Major Histocompatibility Complex II Pathway

Guo, Jin, McLachlan, Sandra M., Rapoport, Basil

Journal:

Year:

2006

Language:

english

File:

PDF, 147 KB

english, 2006

39

Comparison of the sensitivity of the UKCAT and A Levels to sociodemographic characteristics: a national study

Tiffin, Paul A, McLachlan, John C, Webster, Lisa, Nicholson, Sandra

Journal:

BMC Medical Education

Year:

2014

Language:

english

File:

PDF, 310 KB

english, 2014

40

[Endocrine Updates] Graves’ Disease Volume 6 ||

Rapoport, Basil, McLachlan, Sandra M.

Year:

2000

Language:

english

File:

PDF, 34.74 MB

english, 2000

41

Isolation and characterization of a monoclonal human thyroidperoxidase autoantibody of lambda light chain type

Prummel, Mark F., Portolano, Stefano, Costante, Guiseppe, Rapoport, Basil, McLachlan, Sandra M.

Journal:

Molecular and Cellular Endocrinology

Year:

1994

Language:

english

File:

PDF, 784 KB

english, 1994

42

Autoantibodies in the sera of patients with autoimmune thyroid disease recognize a secreted form of human thyroid peroxidase generated in a baculovirus system

Seto, Pui, Nagayama, Yuji, Foti, Daniela, McLachlan, Sandra M., Rapoport, Basil

Journal:

Molecular and Cellular Endocrinology

Year:

1993

Language:

english

File:

PDF, 441 KB

english, 1993

43

Autoimmune Response to the Thyroid in Humans: Thyroid Peroxidase-The Common Autoantigenic Denominator

McLachlan, Sandra M., Rapoport, Basil

Journal:

International Reviews Of Immunology

Year:

2000

Language:

english

File:

PDF, 1.66 MB

english, 2000

44

Insight into Graves’ Hyperthyroidism from Animal Models

McLachlan, Sandra M., Nagayama, Yuji, Rapoport, Basil

Journal:

Endocrine Reviews

Year:

2005

Language:

english

File:

PDF, 854 KB

english, 2005

45

The Molecular Biology of Thyroid Peroxidase: Cloning, Expression and Role as Autoantigen in Autoimmune Thyroid Disease*

McLACHLAN, SANDRA M., RAPOPORT, BASIL

Journal:

Endocrine Reviews

Year:

1992

Language:

english

File:

PDF, 2.92 MB

english, 1992

46

Sex, Genetics, and the Control of Thyroxine and Thyrotropin in Mice

McLachlan, Sandra M., Hamidi, Sepehr, Aliesky, Holly, Williams, Robert W., Rapoport, Basil

Journal:

Year:

2014

Language:

english

File:

PDF, 486 KB

english, 2014

47

Thyrotropin Receptor Autoantibodies in Serum Are Present at Much Lower Levels Than Thyroid Peroxidase Autoantibodies: Analysis by Flow Cytometry 1

Jaume, Juan Carlos, Kakinuma, Ayumu, Chazenbalk, Gregorio D., Rapoport, Basil, McLachlan, Sandra M.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

1997

Language:

english

File:

PDF, 243 KB

english, 1997

48

Presence of Interleukin 4 or Interleukin 10, but Not Both Cytokines, in Pancreatic Tissue of Two Patients with Recently Diagnosed Diabetes Mellitus Type I

Farilla, Loredana, Dotta, Francesco, Mario, Umberto Di, Rapoport, Basil, McLachlan, Sandra M.

Journal:

Year:

2000

Language:

english

File:

PDF, 560 KB

english, 2000

49

Cytokine Profiles of In Vivo Activated Thyroid-Infiltrating T Cells Cloned in the Presence or Absence of Interleukin 4

Guo, Jin, Rapoport, Basil, McLachlan, Sandra M.

Journal:

Year:

1997

Language:

english

File:

PDF, 669 KB

english, 1997

50

Insight into Screening Immunoglobulin Gene Combinatorial Libraries in a Phage Display Vector: A Tale of Two Antibodies

Kakinuma, Ayumu, Portolano, Stefano, Chazenbalk, Gregorio, Rapoport, Basil, McLachlan, Sandra M.

Journal:

Year:

1997

Language:

english

File:

PDF, 992 KB

english, 1997